标题: Synthesis and biological evaluation of novel hybrids of highly potent and selective alpha4beta2-Nicotinic acetylcholine receptor (nAChR) partial agonists.
作者:Zhang, HK[1,2,3];Eaton, JB[4];Fedolak, A[5];Gunosewoyo, H[7];Onajole, OK[1];Brunner, D[5];Lukas, RJ[4];Yu, LF[1,6]
作者全称:Zhang, Han-Kun[1,2,3];Eaton, J. Brek[4];Fedolak, Allison[5];Gunosewoyo, Hendra[7];Onajole, Oluseye K.[1];Brunner, Dani[5];Lukas, Ronald J.[4];Yu, Li -Fang[1,6] 更多
通讯作者地址:Kozikowski, AP (reprint author), Univ Illinois, Dept Med Chem & Pharmacognosy, 833 South Wood St, Chicago, IL 60612 USA.; Yu, LF (reprint author), East China Normal Univ, Shanghai Engn Res Ctr Mol Therapeut & New Drug De, Sch Chem & Mol Engn, 3663 North Zhongshan Rd, Shanghai 200062, Peoples R China.
出版年:2016
卷:124
页码:689-697
关键词:Antidepressant-like effects; Hybrids; Partial agonists; α4β2-nAChRs
摘要:We previously reported the cyclopropylpyridine and isoxazolylpyridine ether scaffolds to be versatile building blocks for creating potent alpha 4 beta 更多
收录类别:SCOPUS;SCIE;PubMed
Scopus被引:2
当年影响因子:4.519
5年影响因子:3.865
JCR分区:Q1
资源类型:外文期刊论文
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scopus被引: 2

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